Cyclops are a huge humanoid species, larger than Shi'ar and Humans, possessing green, grey, or tan skin; and distinctive in possessing only one eye. Their original homeworld was in the Old Universe, although various Wormholes connect that planet to a variety of planets and moons within the Pocket Universe.

Cyclops traditionally have subscribed to a form of monotheism, so in the Pocket Universe they have converted wholesale to the Church of the True God, both the official Church based on Chandilar and the local and splinter sects promoting True God worship.

In the New Shi'ar Imperium, a handful of Cyclops have won seats in the Assembly of Alien Races.

A mutant subspecies of Cyclops is the Mindclops.